Disturbed Copper Bioavailability in Alzheimer's Disease
نویسندگان
چکیده
منابع مشابه
Disturbed Copper Bioavailability in Alzheimer's Disease
Recent data from in vitro, animal, and human studies have shed new light on the positive roles of copper in many aspects of AD. Copper promotes the non-amyloidogenic processing of APP and thereby lowers the Aβ production in cell culture systems, and it increases lifetime and decreases soluble amyloid production in APP transgenic mice. In a clinical trial with Alzheimer patients, the decline of ...
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ژورنال
عنوان ژورنال: International Journal of Alzheimer's Disease
سال: 2011
ISSN: 2090-0252
DOI: 10.4061/2011/345614